Star clusters are destined to evaporate eventually. <br />
I will discuss the disruption mechanisms of star clusters in detail, <br />
and talk about the dynamical evolution of globular cluster systems <br />
in the Milky Way and Virgo Cluster Galaxies.<br />
I will also discuss the initial mass function of the Arches clusters, <br />
one of the most extraordinary clusters found so far, and its evolution. <br />
A novel method to estimate the low-end luminosity function of <br />
a star cluster from a background-limited image will be introduced as well.