In this talk, I will introduce our new simulation suites called TIGRESS, "Three-phase ISM in Galaxies Resolving Evolution with Star formation and Supernova feedback." TIGRESS models a realistic turbulent, magnetized, multiphase ISM in galactic disks with self-consistent treatment for star formation and supernova feedback. I will discuss star formation rates and ISM properties regulated by star formation feedback and the properties of the multiphase outflows driven by SNe. I will also discuss future applications and extensions of TIGRESS.